Postdoctoral Research Fellow in the Department of Pathology at Brigham and Women’s Hospital/Harvard Medical School
Postdoctoral position available to study mechanisms of response to immune checkpoint inhibitors in kidney cancer.
Immunotherapy with immune checkpoint inhibitors (e.g. anti-PD-1/PD-L1 agents) has demonstrated clinical efficacy in metastatic renal cell carcinoma (mRCC). Unfortunately, only a subset of mRCC patients responds to these agents. To guide further clinical development of immune checkpoint inhibitors in kidney cancer, we aim to 1) develop and validate tissue-based predictors of drug response using both genomics approaches and in situ analyses; 2) understand the mechanism of action of PD-1/PD-L1 blockade to facilitate the development of highly active combination regimens.
Requirements: We are seeking a highly motivated applicant with an M.D. or M.D./Ph.D. with formal training in Anatomic Pathology (at least 1 year in residency program) and laboratory experience in pathology and/or molecular biology. Background in bioinformatics/computational biology is desirable. Excellent written and oral communication skillsare required. The candidate must be willing to commit to the position for at least two years.
If interested, please send a cover letter, CV and three references to:
Sabina Signoretti M.D.
Department of Pathology
Brigham and Women’s Hospital
Thorn Building 504A
75 Francis Street
Boston, MA 02115
617-525-7437 (phone)
ssignoretti@bwh.harvard.edu
