{"id":40802263296,"date":"2022-03-30T10:04:47","date_gmt":"2022-03-30T14:04:47","guid":{"rendered":"https:\/\/www.monmouth.edu\/news\/?p=40802263296"},"modified":"2022-04-20T11:45:14","modified_gmt":"2022-04-20T15:45:14","slug":"students-publish-on-effects-of-kumquat-essential-oil-on-cancer-cells","status":"publish","type":"post","link":"https:\/\/www.monmouth.edu\/news\/students-publish-on-effects-of-kumquat-essential-oil-on-cancer-cells\/","title":{"rendered":"Students Publish on Effects of Kumquat Essential Oil on Cancer Cells"},"content":{"rendered":"\r\n<p>Independent undergraduate research performed by Subah Soni &#8217;21, Mruga Parekh &#8217;22, and Jive Jacob &#8217;20 under the direction of Dorothy Lobo, Ph.D., associate professor and chair of the biology department, was recently published as a journal article, &#8220;<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s11010-021-04291-2\">Kumquat essential oil decreases proliferation and activates JNK signaling and apoptosis in HT-1080 fibrosarcoma cells<\/a>,&#8221;\u00a0in the February 2022 issue of &#8220;<a href=\"https:\/\/link.springer.com\/journal\/11010\/volumes-and-issues\/477-2\">Molecular and Cellular Biochemistry<\/a>.&#8221;\u00a0<\/p>\r\n<p>Their research on essential oils, which spanned three years, was sparked by a challenge from James Mack, Ed.D, professor of biology, who has led student research teams to investigate the anti-bacterial properties of essential oils and approached the Lobo research group to see if these oils may also have an effect on cancer.<\/p>\r\n<p>The students were responsible for culturing and treating a variety of cancerous cell lines with kumquat essential oil, which was provided as a gift from Monmouth alumnus Kevin Young &#8217;89. Results demonstrated that treatment of cancer cell lines with kumquat essential oil haltered their proliferation and triggered cell signaling which activated programmed cell death in these cell lines.<\/p>\r\n<p>Soni&#8217;s contributions to the project also resulted in her writing an honors thesis prior to her graduation; she is currently pursuing a master&#8217;s degree in molecular microbiology and immunology at Johns Hopkins. Parekh graduated in January 2022 and has been accepted to dental school for fall 2022. Jacob, who won a travel award in 2019 to present the preliminary work on this project at the national American Society for Cell Biology conference in Washington, DC, is currently applying to medical schools.<br \/><br \/><\/p>\r\n<figure id=\"attachment_40802244174\" aria-describedby=\"caption-attachment-40802244174\" style=\"width: 462px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\" wp-image-40802244174\" style=\"object-position: 46.9375% 54.155%\" src=\"https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-1024x768.jpg\" alt=\"Jive Jacob and Subah Soni\" width=\"462\" height=\"346\" srcset=\"https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-1024x768.jpg 1024w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-300x225.jpg 300w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-768x576.jpg 768w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-1536x1152.jpg 1536w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-2048x1536.jpg 2048w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-1120x840.jpg 1120w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-560x420.jpg 560w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-280x210.jpg 280w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-320x240.jpg 320w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-640x480.jpg 640w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-1400x1050.jpg 1400w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-360x270.jpg 360w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse-150x113.jpg 150w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse.jpg 2133w\" sizes=\"auto, (max-width: 462px) 100vw, 462px\" \/><figcaption id=\"caption-attachment-40802244174\" class=\"wp-caption-text\">Jive Jacob &#8217;20 and Subah Soni &#8217;21 in 2020.<\/figcaption><\/figure>\r\n<p>&nbsp;<\/p>\r\n<figure id=\"attachment_40802263876\" aria-describedby=\"caption-attachment-40802263876\" style=\"width: 432px\" class=\"wp-caption aligncenter\"><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-40802263876 size-full\" src=\"https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2.png\" alt=\"Mruga Parekh \u201922 works in the lab.\" width=\"432\" height=\"521\" srcset=\"https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2.png 432w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2-249x300.png 249w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2-280x338.png 280w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2-320x386.png 320w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2-360x434.png 360w, https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2022\/03\/MParekh_cells2-124x150.png 124w\" sizes=\"auto, (max-width: 432px) 100vw, 432px\" \/><figcaption id=\"caption-attachment-40802263876\" class=\"wp-caption-text\">Mruga Parekh \u201922 working in the lab.<\/figcaption><\/figure>\r\n","protected":false},"excerpt":{"rendered":"<p>Independent undergraduate research performed by Subah Soni &#8217;21, Mruga Parekh &#8217;22, and Jive Jacob &#8217;20 under the direction of Dorothy Lobo, Ph.D., associate professor and chair of the biology department, was recently published as a journal article, &#8220;Kumquat essential oil decreases proliferation and activates JNK signaling and apoptosis in HT-1080 fibrosarcoma cells,&#8221;\u00a0in the February 2022 [&hellip;]<\/p>\n","protected":false},"author":1281,"featured_media":40802263705,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[104,191,423,170],"tags":[],"person":[2411],"audience":[],"school":[119,68],"program":[],"class_list":["post-40802263296","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-academic-excellence","category-personalized-education","category-faculty-perspectives","category-research","person-dorothy-lobo","school-biology","school-school-of-science"],"squareimage":{"id":40802244174,"rendered":"<img width=\"2133\" height=\"1600\" style=\"object-position: 46.9375% 54.155%\" src=\"https:\/\/www.monmouth.edu\/news\/wp-content\/uploads\/sites\/16\/2020\/01\/Jive_Subah_WhiteHouse.jpg\" class=\"attachment-full size-full\" alt=\"Jive Jacob and Subah Soni\" decoding=\"async\" loading=\"lazy\" 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