NURSINGPROFESSOR’S RESEARCH FINDINGS PRESENTED AT THE AMERICAN ACADEMY OF NEUROLOGY
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Fraser PhD, RN, ACNS-BC, associate professor and graduate faculty, Marjorie K.
Unterberg School of Nursing and Health Studies, presented interim data from a
prospective study evaluating spasticity in patients with multiple sclerosis who
transitioned from interferon-beta treatment to glatiramer acetate [GA]
injection. The findings were presented Thursday, April 26, 2012 at the 64th
Annual Meeting of the American Academy of Neurology (AAN) in New Orleans,
prospective longitudinal survey research study is evaluating 110 participants
utilizing the Multiple Sclerosis Spasticity Scale (MSSS-88), the Performance
Scales, and a sociodemographic questionnaire completed when transitioning
between treatments and at month six. Inclusion criteria require that
participants had stopped interferon-beta treatment within 30 days; were about
to start, or started glatiramer acetate injections within the previous 21 days;
had spasticity; and able to ambulate with unilateral support or without. Of the
52 participants, 35 percent were taking medication for spasticity prior to
enrollment and during the six month period.
results for the first 52 of 110 participants revealed a significant reduction
in muscle stiffness, pain and discomfort, and the effect of spasticity on the
ability to walk, body movements and activities of daily living. Improvement was
also found in reduction of total spasticity scores during the six month period.
findings suggest that spasticity may be reduced for MS patients who discontinue
IFN-β and transition to GA. The results of the study with the total sample are
expected to be completed by October 2012.
more information, contact Professor Fraser at 732-263-5294
Academy of Neurology Poster Session P07.074: A Prospective Study of Spasticity
in Individuals with Multiple Sclerosis (MS) in Transition from Interferon-Beta
to Glatiramer Acetate
contact: Petra Ludwig at 732-263-5507